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The department carries forward a rich legacy as its first departmental chair was the renowned Physiologist Padma Vibhushan Dr. Autar Singh Paintal who also happened to be the first Principal of the institution. He was the first Indian Physiologist to become a Fellow of the Royal Society, London, was former Director General of the Indian Council of Medical Research and founded the Society of Scientific Values. In 1976, Dr K N Sharma joined the UCMS, as Professor of Physiology. He was a great teacher and researcher, a competent administrator, had a strong work ethic and was actively involved in medical education (need based teaching-learning and assessment strategies), development of innovative teaching methods, and medical curriculum development in India & abroad. Soon, he became Principal of UCMS and shaped the great institute to its present glory. Professor Dr. Farah Khailq currently heads the department. The department is actively engaged in the basic and applied research in the fields of cardiovascular, respiratory, neurophysiology, clinical electrophysiology including evoked potential, yoga research, academic medicine, clinical medical ethics and health humanities. The department assists in the teaching of health professions education for MBBS, BSc Nursing, and BSc Physiotherapy, BSc Medical Technology, BSc Radiography and open classes.

The order of designation is as follows : HOD, Director Professor, Professor, Associate Professor, Assistant Professor.
The names with in each designation is in alphabetical order and not in order of seniority.